• 2 different types of illness

    • meningitis

    • sepsis

  • 13 serotypes

    • most infections B or C strains
  • meningitis also strep pneumo of H.influenzae

  • highers \<1yo

  • 1-4yo

  • another peak 15-19yo

Infection

  • prodromal

    • non-specific symptoms

      • acute fever

      • vomiting

      • nausea

      • lethargy

      • irritability

      • refusing food/drink

      • headahce

      • muscle/joint pain

      • resp symptoms

    • dry cough = influenza compared to meningococcal disease

  • classical signs

    • maybe absent

    • within first 4-6hrs

  • meningitis

    • photophobia

    • severe headahce

    • focal neural difict

    • drowsiness/confusion

    • seizures

    • Kernig’s sign

      • supine with leg raised at hip and bent 90deg

      • pain or resistance with furter extension

    • Brudzinski sign

      • postiive if involuntary bending/flexion when in supine position ha dhead passively raised or lifted
    • low sensitivity/high specificity

  • sepsis

    • rash

      • non-banching
    • rapidly deteriorating condition

    • limb/joint pain

    • cold hands/feet

    • capillary refill time > 2sec

    • unusual skin colour

    • tachycardia

    • rigors

  • how quickly disease progression

  • clinical judgement - does seem more severe

  • level of parental/caregiver concern

Management

  • refer

  • Benzylpenicillin

    • \<1yo 300mg IV/IM

    • 1-9yo 500mg IV or IM

    • >10yo 1.2g IV/IM

  • Ceftriaxone 50-100mg/kg up to 2g

if cannot be ruled out:

  • plan review 4-6hrs

  • advise patient to return to practice in 12-24hrs or any time if concern

  • not being sent home alone

  • check on patient every hour for next 6-12hours